What if I told you I discovered
a Bio-Tech company with a new drug that could reduce the number of cancer deaths
in the US by 43,000 annually, reduce colon cancer by 50%, and breast and ovarian
cancer by 30%. Would you be impressed? What if I then told you this same drug
could safely prevent or alleviate the following medical conditions:
Osteoporosis, Hypertension, Cardiovascular disease, Cancer, Depression,
Epilepsy, Type One Diabetes, Insulin resistance, Autoimmune Diseases, Migraine
Headache, Polycystic Ovary Disease (PCOS), Musculoskeletal and bone pain,
Psoriasis, and Rheumatoid Arthritis, Inflammatory Bowel Disease (Cohn’s),
chronic lymphocytic leukemia (CLL), as well as improve calcium absorption and
reduce hip fractures.
Would you then be even more impressed, and rush out to buy the company stock and
get rich quick? Of course you would, but we don’t need a new Bio-Tech drug to
do this, because, all of the above benefits can be obtained with Vitamin D, an
inexpensive vitamin which is free with sun exposure.
Deficiency in Florida, Surely You must Be Joking:
We all know it’s a fact: Everyone in Florida gets plenty of Vitamin D from the
Florida Sun. This would have been true except for the fact that as Floridians,
we are all told to avoid the sun to prevent solar skin damage (brown wrinkling)
and to avoid skin cancer.
So the question remains, do we get enough Vitamin D from sun exposure? To answer
this question, we actually measured blood Vitamin D levels, and we were
surprised to discover that the majority showed Vitamin D deficiency (less
than 20 ng/ml), or insufficiency (less than 40 ng/ml).
What if you are not fortunate to live in sunny Florida and you live up north
above the Mason Dixon Line, in Boston, New York, Chicago, Canada or Scandinavia?
Northern latitudes have an even more serious vitamin D deficiency because of the
lack of UV sunlight during the winter months. The angle of the sun through the
atmosphere closes off the UltraViolet Light from reaching the earth.
An Epidemic of
Vitamin D Deficiency
Vitamin D deficiency has been reported in 57% of 290 medical inpatients in
Massachusetts, 93% of 150 patients with overt musculoskeletal pain in Minnesota,
48% of patients with Multiple Sclerosis, 50% of patients with lupus and
fibromyalgia, 42% of healthy adolescents, 40% of African American Women, and 62
% of the morbidly obese, 83% of 360 patients with low back pain in Saudi Arabia,
73% of Austrian patients with Ankylosing Spondylitis, 58% of Japanese girls with
Graves's Disease, 40% of Chinese adolescent girls, 40-70% of all Finnish medical
Vitamin D excess and toxicity requires daily dosage in excess of 40,000 units
over a period of months, so 5,000 units a day is safe and far below the level
needed to develop vitamin D toxicity. Remember Vitamin D is a fat soluble
vitamin, so toxicity is possible with massive doses over long periods of time.
Vitamin D toxicity causes elevated calcium levels. That’s why Vitamin D
supplementation should done only under your physician’s supervision with
monitoring of serum 25-Hydroxy Vitamin D levels.
Maps of UV Sunlight exposure correlate with incidence of Cancer and Multiple
If you take NASA space satellite photos of North America and color code the UV
sunlight exposure as Dr. Grant has done on his
web site, Sunarc.org, you will see a
pattern remarkably similar to the incidence of cancer and multiple sclerosis.
This is thought to be due to differences in Vitamin D levels. The farther north
with less sun exposure and lower Vitamin D levels, there is an increased
incidence of cancer and multiple sclerosis.
By, or Associated With Vitamin D Deficiency:
Again here is the list: Osteoporosis, Hypertension, Cardiovascular disease,
Cancer, Depression, Epilepsy, Type One Diabetes, Insulin resistance, Autoimmune
Diseases, Migraine Headache, PolyCystic Ovary Disease (PCOS), Musculoskeletal
and bone pain, Psoriasis, and chronic lymphocytic leukemia (CLL).
The current recommendation for Vitamin D deficiency in those people who must
avoid the sun is 5,000 IU of Vitamin D per day which costs 5 cents a day..
Vitamin D is not
really a Vitamin, it is a Hormone.
Like all other steroidal hormones, vitamin D is made from a cholesterol
precursor, converted in the skin by sunlight. Like all other hormones, Vitamin D
enters the nucleus of the cell and binds to the DNA where it gives a message to
the DNA to manufacture proteins.
Image: Vitamin D Chemical
Structure Courtesy Wikipedia
Vitamin D And
A review by Dr. Brown reported that Vitamin D supplementation prevented the
development and progression of experimental autoimmune encephalitis, an animal
model of MS, in mice. A large, prospective, cohort study found that vitamin D
supplementation was associated with a 40% reduction in the risk of developing
MS. Four small, noncontrolled studies suggested that vitamin D supplementation
may decrease exacerbation of MS symptoms.
MRI studies of multiple sclerosis lesions show improvement during summer months
and worsening during winter months suggesting a Vitamin D link.
Vitamin D and
A four-year clinical trial, involving 1,200
women found those taking the vitamin had about a 60-per-cent reduction in cancer
incidence, compared with those who didn't take it, a drop so large — twice the
impact on cancer attributed to smoking — it almost looks like a typographical
error. The study was done by professor of medicine Robert Heaney of Creighton
University in Nebraska and was published in June 2007.
and Total Mortality
A 2007 meta-analysis review of 18 studies showed a reduction in all cause
mortality of about 10% in people supplementing with commonly used doses of
Supplementation for Adults
The RDA in America is only 400 IU per day, yet current research suggests that
our daily Vitamin D requirement is closer to 4,000 to 5,000 IU. Twenty minutes
of Sun exposure will give us ten to twenty thousand IU of Vitamin D.
Adult Supplementation with Carlson’s Cod Liver Oil can provide Vitamin D along
with Vitamin A . However, for an intake of 5,000 IU vitamin D per day,
inexpensive Vitamin D3 capsules are widely available for about 5 cents a day. We
provide these as a convenience to our office patients.
Testing at the Lab
Optimal serum 25-hydroxyvitamin D values are 45-50 ng/ml. Below 40 ng/ml is
called Vitamin D insufficiency, and below 20 ng/ml is deficiency.
Our health care system is in crisis. We are spending billions on expensive
procedures like coronary artery bypass and organ transplantation, yet
measurements of health are lower than other countries that spend less. In terms
of getting more bang for your health care buck, Vitamin D testing and
supplementation for the population is one solution which is guaranteed to
improve overall health of the population at a ridiculously low cost.
The cost saving in reduced cancer rates, and lower osteoporotic fracture rates
would be enormous, and we would all enjoy improved health. My goal as a
physician in our community is to improve the health of of our community, and
Vitamin D testing and supplementation is one way to achieve that goal with no
adverse side effects and enormous cost savings.
Prospects for Vitamin D Nutrition. Vitamin D and Human Evolution Clinical
relevance of higher vitamin D intakes, Toxicology of Vitamin D Reinhold Vieth,
Pathology and Laboratory Medicine, Mount Sinai Hospital, and Laboratory Medicine
and Pathobiology, University of Toronto Calgary AB, Oct 13 2005. Highly
recommended Web Cast video presentation on Vitamin D by Dr. Vieth
Munger, Levin,. Hollis, PhD Howard, Ascherio, Serum 25-Hydroxyvitamin D Levels
and Risk of Multiple Sclerosis JAMA. 2006;296:2832-2838 Epidemiological and
experimental evidence suggests that high levels of vitamin D, a potent
immunomodulator, may decrease the risk of multiple sclerosis.
Michael F Holick, Vitamin D: importance in the prevention of cancers, type 1
diabetes, heart disease, and osteoporosis American Journal of Clinical
Nutrition, Vol. 79, No. 3, 362-371, March 2004
Holick , Michael F VITAMIN D AND HEALTH IN THE 21ST CENTURY: BONE AND BEYOND,
Sunlight and vitamin D for bone health and prevention of autoimmune diseases,
cancers, and cardiovascular disease American Journal of Clinical Nutrition, Vol.
80, No. 6, 1678S-1688S, December 2004. Excellent full text article review.
http://www.ncbi.nlm.nih.gov/pubmed/12800453 The effect of vitamin D3 on insulin secretion and peripheral insulin
sensitivity in type 2 diabetic patients. Int J Clin Pract 2003; 57(4): 258-61.
Borissova AM, Tankova T, Kirilov G, Dakovska L, Kovacheva R.
http://www.ncbi.nlm.nih.gov/pubmed/2643969 Lind L et al. “Reduction of blood pressure during long-term treatment
with active vitamin D (alphacalcidol) is dependent on plasma renin activity and
calcium status. A double-blind, placebo-controlled study.” Am J Hypertens 1989;
http://www.ncbi.nlm.nih.gov/pubmed/10939587 Embry AF, Snowdon LR, Vieth R.Ann Neurol. 2000 Aug;48(2):271-2.
Vitamin D and seasonal fluctuations of gadolinium-enhancing magnetic resonance
imaging lesions in multiple sclerosis.
Vitamin D and calcium supplementation reduces cancer risk: results of a
American Journal of Clinical Nutrition, Vol. 85, No. 6, 1586-1591, June 2007
Joan M Lappe, Dianne Travers-Gustafson, K Michael Davies, Robert R Recker and
Robert P Heaney.
Vitamin D Supplementation and Total Mortality A Meta-analysis of Randomized
Controlled Trials Philippe Autier, MD; Sara Gandini, PhD Arch Intern Med.
2007;167:1730-1737. Conclusions Intake of ordinary doses of vitamin D
supplements seems to be associated with decreases in total mortality rates.
Vitamin D and calcium supplementation reduces cancer risk: results of a
randomized trial. American Journal of Clinical Nutrition, Vol. 85, No. 6,
1586-1591, June 2007 Joan M Lappe, Dianne Travers-Gustafson, K Michael Davies,
Robert R Recker and Robert P Heaney.
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